Director, Medicinal Chemistry

Director, Medicinal Chemistry

Job Title: Director, Medicinal Chemistry
Contract Type: Permanent
Location: San Francisco, California
Salary: Negotiable
Start Date: ASAP
Reference: 432643_1558133133
Contact Name: Reece Mitellas
Contact Email:
Job Published: May 17, 2019 23:45

Job Description

As a member of the chemistry team, lead a strong group of medicinal chemists working on multiple lead optimization programs

* Direct efforts for the design and implement strategies for the synthesis of novel molecules in diverse optimization efforts and advance targets to candidate selection

* Work closely with the biology group and proactively evaluate new biological targets and start new programs

* Effectively lead and manage the productivity of cross-functional small molecule drug discovery teams to advance aggressive corporate goals

* Provide regular assessment of project status to multidisciplinary scientific team and senior management

* Lead by example and contribute to the writing of patents applications, reports, and scientific publications


* PhD in synthetic organic chemistry with a minimum of 10 years of medicinal chemistry experience in biotech/pharmaceutical industry

* Proven ability to provide mentorship to both highly experienced staff and new hires

* Knowledgeable and experienced in the broad area of small molecule drug discovery with insightful understanding of emerging industry trends

* Demonstrated success in leading small molecule drug discovery programs from project inception through lead optimization, preclinical evaluation to development candidate nomination

* Enthusiastic and high energy leader with outstanding scientific expertise, conceptual thinking, problem solving skills; ability to motivate teams to expeditiously change course as required in a fast-paced organization

* Proven track record of partnering with multi-disciplinary team setting through expertise in Chemistry, Biology, DMPK, Pharmacology and Toxicology and others

* Must have excellent oral and written communication skills

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