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Senior Director Nonclinical Pharmacology

Posted about 1 month ago

​EXCLUSIVE Senior Director level leadership opportunity with clinical-stage, publicly traded biotech in Seattle!

We are exclusively working this search for a Senior Director to lead the NonClinical team, working alongside the heads of Discovery, Process Development, and Clinical Development with direct exposure to the executive team. Candidates with strong aptitude and lighter experience level will be considered for a Director title and similar responsibilities.

The role will be responsible for overseeing Pharmacology and Pharmacokinetics, including directing non-clinical safety studies, toxicology studies, and assay development to assess drug potency, and anti-drug antibodies in non-clinical and clinical settings. You'll be managing a matrix style team with direct and dotted line reports as well as consultants and CRO partners.

Detailed responsibilities include, but are not limited to:

  • Leading non-clinical pharmacology and safety assessment efforts

  • Directing the Assay Development team responsible for evaluating drug potency, and supporting PK and ADA evaluation in preclinical & clinical development

  • Evaluating species justification to support non-clinical safety studies

  • Directing toxicology study design and execution through external partners

  • Contributing to the development of IND submission materials, supported by regulatory experts

For the Senior Director level, candidates should have a PhD in Immunology or related field with 12+ years of industry experience in non-clinical assessment of protein therapeutics to support IND enabling studies. Less experienced candidates will be considered for the Director level with the opportunity to progress quickly within the hierarchy. This role reports to the CSO and interfaces with all leadership and executive stakeholders in the company.

Interested parties should apply now for a confidential conversation! This role is a top priority, and will be involved in upcoming hires for the team. For any additional inquiries please reach out to